We also face the same issue. For our case we are using iTMSTransporter 3.3.0.16
What we try is if we run
#> /usr/local/itms/bin/iTMSTransporter -m upload -f ./upload.itmsp
then we will see the "Invalid provisioning profile signature"
but if we run
#> /usr/local/itms/bin/iTMSTransporter -m upload -assetFile ./upload.itmsp/upload.ipa
then the file will upload successfully.
Based on the log, looks like the error is from Apple 's web service "Using operation named: validateAssets"