I am having a similar problem. We run a local Apache Tomcat server for our development environment. At the point that the Apache Server usually starts up, I get the following error:
Exception in thread "main" java.net.ConnectException: Operation timed out (Connection timed out)
at java.net.PlainSocketImpl.socketConnect(Native Method)
at java.net.AbstractPlainSocketImpl.doConnect(AbstractPlainSocketImpl.java:350)
This has worked for over 6 years BEFORE upgrading to Sequoia.
We run on 127.0.0.1 at port 8080 if that makes any difference.
Oddly enough, for reasons I don't understand, it will start up occasionally. I have no idea why.