I am writing this to report the same issue, I am using M1 Macbook Air, my USB hub brands are QPNP and HyperDrive. After upgrading to Monterey, most ports are not working as expected. It can detect the microphone when attached to USB hub, however, it uses internal microphone instead of the external microphone, I can confirm this when I use the single USB adapter instead of the USB hub, it works with USB adapter with no issue. Please help fix this issue, thank you!