Has anyone resolved this problem? I'm having exactly the same issue after upgrading to Big Sur beta. Tried reinstalling Office, resetting fonts, nothing works. For example in email I don't see the text unless I click "reply" (the text of the original mail is the visible in the new reply window). In excel I don't see the cell contents unless I select everything and change a font of all cells - Calibri, Arial, many other don't work. Lucida Grande does work.