I have the same problem with my Brand new M1 16" mac on 12.0.1 Monterey. I have multiple mouses (briefcase, work office, home office, etc) and the problem persists no matter WHICH mouse I use. The only thing that (usually) fixes it is to turn the mouse off and then back on, or go into bluetooth, "forget" the mouse, and reinstall it.
That said, this happens multiple times a day. VERY frustrating!
Brian_Boca
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