FYI - Since updating to Beta 5, I can once again use Time Machine to backup to an external drive configured with APFS.
After Time Machine started working again in Beta 4, I unfortunately updated my exterrnal drive to APFS, which was a mistake that I read about too late. It killed Time Machine backups. I was tempted to buy a new external HDD, but I figured Apple would eventually want APFS to be used everywhere. Now, with Beta 5 Time Machine again works with that APFS externall HDD.