When nightshift mode is enabled the computer does not respond to any input commands and the mouse/pointer turns into a permanent beach ball until I unplug my LG Ultrafine 5k, when I disable nightshift everything returns to normal.
Tried to:
Reset NVRAM, SMC same results
macOS Sierra 10.12.4 Beta 1 (16E144f)
MacBook Pro (15-inch, Late 2016)
2.9 GHz
Radeon 460