PS: These are the log entries that seem relevant. The last one is about an unresolved rpath.
2022-05-01 08:48:26.907551+0200 0x12fa3c Default 0x0 694 2 ***: (LaunchServices) [com.apple.launchservices:default] Non-fatal error enumerating at , continuing: Error Domain=NSCocoaErrorDomain Code=260 "The file “PlugIns” couldn’t be opened because there is no such file." UserInfo={NSURL=PlugIns/ -- file:///Volumes/Nodelab/nodelab.app/Contents/, NSFilePath=/Volumes/Nodelab/nodelab.app/Contents/PlugIns, NSUnderlyingError=0x7fdca7184270 {Error Domain=NSPOSIXErrorDomain Code=2 "No such file or directory"}}
2022-05-01 09:27:56.604669+0200 0x12fa3c Default 0x0 694 2 ***: (LaunchServices) [com.apple.launchservices:default] Non-fatal error enumerating at , continuing: Error Domain=NSCocoaErrorDomain Code=260 "The file “PlugIns” couldn’t be opened because there is no such file." UserInfo={NSURL=PlugIns/ -- file:///Volumes/Nodelab/nodelab.app/Contents/MacOS/PySide6/Qt/lib/QtWebEngineCore.framework/Helpers/QtWebEngineProcess.app/Contents/, NSFilePath=/Volumes/Nodelab/nodelab.app/Contents/MacOS/PySide6/Qt/lib/QtWebEngineCore.framework/Helpers/QtWebEngineProcess.app/Contents/PlugIns, NSUnderlyingError=0x7fdca6784360 {Error Domain=NSPOSIXErrorDomain Code=2 "No such file or directory"}}
2022-05-01 09:27:56.604684+0200 0x12fa3c Default 0x0 694 2 ***: (LaunchServices) [com.apple.launchservices:default] - 45683955: Checking whether application is managed at file:///Volumes/Nodelab/nodelab.app/Contents/MacOS/PySide6/Qt/lib/QtWebEngineCore.framework/Helpers/QtWebEngineProcess.app//org.qt-project.Qt.QtWebEngineProcess
2022-05-01 09:29:06.716051+0200 0x140134 Error 0x0 581 0 XprotectService: [com.apple.xpr
otect:xprotect] File /Applications/nodelab.app/Contents/MacOS/PySide6/Qt/lib/QtWebEngineCore.framework/Versions/A/Helpe
rs/QtWebEngineProcess.app/Contents/MacOS/QtWebEngineProcess failed on rPathCmd /Users/qt/work/install/lib/QtOpenGL.fram
ework/Versions/A/QtOpenGL (rpath resolved to: (path not found), bundleURL: /Applications/nodelab.app)