Apparently, the new version of Instruments records traces of other processes that utilize the GPU while your process is running. This adds a lot of noise to the profiling data.
nullspace
Users receive reputation points by contributing quality content to the forums.
Posts include post and replies published on the forums.
Post authors can mark replies as Accepted to indicate successful solutions.
Apple Developer Forums admins can mark replies as Apple Recommended to indicate an approved solution
Post
Replies
Boosts
Views
Activity
This just adds a lot of noise to the profiling data and would be nice to configure it.
What app is this? looks like it's using OpenGL, which is deprecated starting macOS 10.14.
MTLDevice instance should have access to architecture: https://developer.apple.com/documentation/metal/mtldevice/4195341-architecture