Yesterday (Nov. 13), I upgraded my OS to Mac OS 11.01 Big Sur. Everything worked fine, until a few minutes later that I started to experience a flickering in the bottom of the screen, that replicated a ghost image of the top section of the screen. I tried several things but nothing worked. Keeping trying, I was looking into the "Activity Monitor", and simply guessing I decided to kill the processes "mds stores", "mds" and some related to "md-" processes (which actually showed a high rate of energy consumption). To my surprise, after killing this processes, the screen flickering stopped. After this, my screen works fine for several minutes, until the flickering starts again. I confirm that I can solve the flickering if keeping killing the "mds" processes (I understand this process is related to the metadata indexing in spotlight, and my sometimes consumes important amount of energy).
I hope this is useful information for Apple engineers to find a solution for this problem. Meanwhile, at least for me, killing the "mds" processes solves (for 20-30 minutes at least) a temporal solution for the screen flickering. A final solution is needed urgently.