I was getting this gradually creeping in during the day - clicking and crackling while listening to Spotify. Following previous advice on closing apps I just quit Firefox which had 96 tabs open and the crackling disappeared instantly. I still have loads of apps open including Android Studio, mail, chrome etc Restarting FF with the same number of tabs as before didnt interfere with the music for a while - but it started to creep in over time. I never switch my Mac off just put it to sleep. So most likely an accumulated memory issue, or one of the tabs played audio which was interfering with Spotify. None of the other fixes work except for the reboot which effectively restarts Firefox anyway. This was on a MBP 14" 2021 32GB M1 Max