I use Xcode 12.0.1 (12A7300), testing on iOS14 devices and I have the exact same issue. I have noticed that the constraints are being reset at the time the app goes in the background.
For now, to temporarily fix the issue, I check if the contraints are valid in the layoutSubviews() function in my UITableViewCell. If not, I set them to what they are supposed to be.
If you have solved the issue in any other way I would highly appreciate your update :)