It's so annoying. I have the exact same setup at home as well at the office. The only exception is, that my two Lenovo ThinkVision P24h-10 monitors at the office are the newer 75Hz variant. At home I have absolutely no problem. At the office my MacBook Pro 16" (AMD Radeon Pro 5300M 4 GB) crashes all the time. Exact same pattern as everyone here. I plug in the monitors wake up my MacBook… woosh… Fans spins — Kernel Panic.
Happens since 11.13. It's nice that the problem is fixed in 12 Beta but I need this machine for work so beta software is pretty much non acceptable.