I was also looking for answers for some of these questions. Specifically, I was trying to compile and use Infer analyzer tool (https://github.com/facebook/infer) - Infer uses some custom clang compiler for C++ analysis. Compiling custom clang plugin on M1 wasn't successful - there was some linking issue with LLVM. So, I tried to run Infer with custom clang compiled on Intel Mac. I've just run make install on M1. When actually running Infer executable in Terminal (run in Rosetta 2) it reports "Fails pinning to CPU". An important thing to mention is that Infer requires some dependencies from Xcode 11.5 (there are issues with more recent versions). As there are quite few dependencies I guess an issue can be anywhere, but I am not sure how to debug this kind of issue. Is there anyone who has similar issue?