Dear friends, I am happy to disclose that the solution is way simpler than bashing the terminal: search for Activity Monitor.app in spotlight find your app that threw an 10668 or similar error (i.e. Chrome) double click it in the list, so that a dialog window opens where you click Quit then another dialog window where you have to click Force Quit Try reopening your application (i.e. Chrome) and it work just fine As a result of updating your OS some files must be trapped in limbo and references are broken. Now, when you force quit, these files and references for this running instance must be built anew. Cheers and greetings from Zurich, Switzerland