Python issues can be fixed (and usdpython command line tools works correctly) with the recommendation given on this post which advises to install an specific version of python directly (avoiding homebrew).
Now, Reality Converter app seems to have issues with sandboxing on Monterey as it outputs this to the console every time a conversion is attempted
Sandbox: Python(1239) deny(1) file-write-create /Applications/Reality Converter.app/Contents/XPCServices/RealityConverterService.xpc/Contents/SharedSupport/usdpython/USD/lib/python/pxr/Ndr/__pycache__
(MacBook Pro M1 Pro, macOS 12.3.1, Reality Converter beta 4)
CristianAtmonstar
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