I had the same issue. Any video with that matter, YouTube, Netflix or any other, the video was not played in the Safari in this beta. On the other hand, the same video does play in other applications like Google Chrome and Firebox.
You can change this setting. All you have to do is disable "Develop tab -> Experimental features -> VP9 decoder", and then restart Safari. This would help your videos work normally!
Good luck developers! 👍