Can I interrupt encryption of a large external disk without serious loss?

I am running the encryption of a 4TB external drive, nominally under Time Machine. If I interrupt the task, can it subsequently pick up without substantial loss of the earlier work

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User-centric queries/comments such as this are perhaps best put to Apple's public community support forums, run by AppleCare, and/or Apple's twitter support account, vs. risking off-topic here in the DevForums, thanks and good luck.

https://support.apple.com/