Security running DOSBox on MacOS?

General security question. Are there security concerns running DOSBox natively on MacOS? I'm not sure if Apps are run inside some user jail that prevents the app from modifying user data outside the application or other MacOS files.

I've been running DOSBox inside a VirtualBox Debian VM, basically because I have slightly higher trust in VirtualBox packaging than DOSBox. Unfortunately, sound and mouse movement is choppy, which makes me consider running DOSBox natively on MacOS. I think about Keychain access to my accounts and if DOSBox presents a security concern. Note, I run few few open source products on MacOS natively, mostly inside Linux VM instances for this reason.

Unsure if these are the best tags for such a question.