Audio Crackling in Playback

when using my 2015 Version MacBook pro plugged into my audio interface for playback I'm getting a crackling noise. When I playback directly from my mac with headphones or through the CPU speakers it plays fine. I've tried replacing the interface, cords & wires and still no luck. if I cant fix this I'll probably sell my mac.

Audio Crackling in Playback
 
 
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