As mentioned in Stack Overflow, try Force Quit Application when XCode is running.
option + command + esc
Restarting XCode didn't work for me, but forcing it to quit did.
epatton
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Same assert with iOS 13.0. I stepped through the code and TARGET_OS_SIMULATOR and TARGET_IOS defines are set.
Correction to the above: I tried the simulators
iphone 11, 12 and iPad Gen 9 with iOS 15.4
I'm downloading the iOS 13.0 to try next.