Can I use string entered in _locale / en / messages.json in the popup.js script file?

I have been selling paid ad blocking apps for the past 6 years using the content blocker API. It has sold over 400,000 products. However, I would like to talk about the following issues. To block resources or pop-ups in iframes in the site, add the address of the currently accessed site to the if-domain value. But in practice this is not efficient. Most video players use iframes. When you press the play button in an iframe, a pop-up window often appears. There are several representative companies for video players (iframes). We would like to register the address used for the video player (iframe) globally and block it, but this is not possible. It is very cumbersome to add the address of the site used by embedding a video player (iframe) each time. I hope the address value of if-domain can be used in iframe. Thank you.