System: MacBook Pro (16-inch, 2019), 64 GB RAM, Elgato Thunderbolt dock, Apple Pro Display XDR
Symptoms: Delayed text while typing, sometimes lost characters, major lag when changing volume or switching Desktops, Thunderbolt dock was often not recognized without connect/disconnect cycling, Sound settings (Speaker/Mic) not retained, Camera not connecting. Much of what you've read on the other 11 pages of this issue. Many restarts, Bluetooth resets and the like.
Prescription: Read JayBizzle's post above. Reset the SMC. See here: https://support.apple.com/en-us/HT201295
Result: MBP is back to running smoothly like in MacOS Catalina. Thanks JayBizzle.