Reply to module map file '/Users/hosein/Library/Developer/Xcode/DerivedData/Sporty-ficshtjjzxcsgkaohfxowaxpyivr/Build/Products/Debug-iphonesimulator/YogaKit/YogaKit.modulemap' not found I am running into the exact same issue with a new M1 macbook pro. I was able to create a brand new React Native project and run it in a simulator no problem so it seems to be an issue with existing projects. Developer Tools & Services Xcode Dec ’20